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[28] Cs2CO3-Promoted Hydrothiolation of ortho-(Alkynyl)Benzyl Bromides for the Construction of 3-Isothiochromene Derivatives, S. Ghosh, S. Savar, R. J. Reddy*, To be Communicated.
[27]-Base-Mediated Convenient Synthesis of Sulfonyl-1,2,3-NH-Triazoles and b-Amidovinyl Sulfones using (E)-b-Iodovinyl Sulfones, N. Sharadha, K.aplai Shravika, R. Pallepogu, R. J. Reddy*, To be Submitted.
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[26]-Substrate-Directed Annulative-Sulfonylation/ Desulfonylation Cascade Using (E)-β-Iodovinyl Sulfones: A Diverse Approach for the Synthesis of Imidazo[1,2-a]pyridines with Sulfone Motifs, Sharadha, N. and Reddy, R. J.* J. Org. Chem. 2025, 90, 15942–15955.
​​​[25]-Metal-Free Four-component Strategy to Access Thioether-Derived Imidazo[1,2-a]pyridines and Imidazo[2,1-b]thiazoles, A. H. Kumari, S. Ghosh, N. S. Veeranagaiah, R. Pallepogu, and Reddy, R. J.* Eur. J. Org. Chem. 2025, 28, e202500394
[24]-Vicinal Thiosulfonylation of ortho-(Alkynyl)-Benzyl Thiosufonates/Sulfurothioates for Direct Synthesis of Sulfonyl-derived Isothiochromenes, A. H. Kumari, H. K., Kumar, J. J., J. Org. Chem. 2025, 90, 3628−3638.
[23]-Transition-Metal-Free Annulation of Sulfonyl-Derived 1,3-Enynes: Simple and Efficient Construction of 2,4-Disubstituted Thiophenes and Vinyl Sulfone-Tethered 1,2,3-NH-Triazoles, Sharadha, N., Kumari, H. K. and Reddy, R. J.* Asian J. Org. Chem., 2024, e202400211.
[22]-Visible-Light-Induced Radical Sulfonylative-Cyclization Cascade of 1,6-Enynol Derivatives with Sulfinic Acids: A Sustainable Approach for the Synthesis of 2,3-Disubstituted Benzo-heteroles, Kumari, H. K., Kumar, J. J., Sharadha, N., Krishna, G. R., and Reddy, R. J.*. ChemSusChem, 2024, e202400227.
[21]-Recent trends in the synthesis and applications of β-iodovinyl sulfones: A decade progress (Review article), Reddy, R. J.* Kumar, J. J. and Kumari, H. K., Org. Biomol. Chem. 2024, 22, 2492-2509.
[20]-Pd(II)-Catalyzed Tandem Cycloannulative-Alkenylation of ortho-Alkynyl-Phenols/ Anilines with (E)-β-Iodovinyl Sulfones: A Direct Strategy to Construct 3-(Vinyl Sulfonyl)-Benzoheterole Derivatives, Reddy, R. J.* Sharadha, N. and Krishna, G. R. J. Org. Chem. 2023, 88, 8889-8903.
[19]-Mn(OAc)3-Mediated Unexpected Cycloannulative-Sulfonyl Migration Cascade using (E)-β-Iodovinyl Sulfones and Ortho-Alkynylphenols: An Expedient Synthesis of Chromene-derived Vinyl Sulfones, Reddy, R. J.* Kumar, J. J. and Kumari, H. K. Org. Lett. 2023, 25, 2207–2212.
[18]-Unified Radical Sulfonylative-Annulation of 1,6-Enynols with Sodium Sulfinates: A Modular Synthesis of 2,3-Disubstituted Benzoheteroles, Reddy, R. J.* Kumari, H. K. and Krishna, G. R. J. Org. Chem. 2023, 88, 1635-1648.
Reddy, R. J.* Kumar, J. J. and Krishna, G. R. Adv. Synth. Catal., 2022, 364, 4080.
[16]-Base-mediated [3+2]-cycloannulation strategy for the synthesis pyrazolo[1,5-a]pyridine derivatives using (E)-beta-iodovinyl sulfones, Reddy, R. J.*, Sharadha, N., Kumari, A. H. Org. Biomol. Chem. 2022, 20, 4331-4337.
​[15]-Solvent-Dependent Mono- and Bis-Thiolation of (E)-beta-Iodovinyl Sulfones with Thiols for Flexible Synthesis of 1,2-Thiosulfonylalkenes and 1,2-Dithioalkenes, Reddy, R. J.* Kumari, A. H., Sharadha, N. and Krishna, G. R., J. Org. Chem. 2022, 87, 3934−3951.
[14]-Diethyl phosphite-mediated switchable synthesis of bis(imidazoheterocycles) derived disulfanes and sulfanes using imidazoheterocycles and octasulfur (Invited), Reddy, R. J.* Shankar, A., Kumar, J. J., Sharadha, N., and Krishna, G. R., New. J. Chem., 2022, 46, 4784-4791.
[13]-Interrupted CuAAC-Thiolation for the Construction of 1,2,3-Triazole-Fused Eight-Membered Heterocycles from O-/N-Propargyl derived Benzyl Thiosulfonates with Organic Azide, Reddy, R. J.* Waheed, Md., Kumari, A. H., and Krishna, G. R., Adv. Synth. Catal. 2022, 364, 319-325.
[12]-Ni–Catalyzed Difunctionalization of Alkynyl Bromides with Thiosulfonates and N-Arylthio Succinimides: A Convenient Synthesis of 1,2-Thiosulfonylethenes and 1,1-Dithioethene, Kumari, A. H., Kumar, J. J., Krishna, G. R., and Reddy, R. J.,*, Synthesis, 2021, 53, 2850–2864.
[11]-Recent Advances in the Synthesis and Applications of beta-Keto Sulfones: New Prospects for the Synthesis b-Keto Thiosulfones (Review article), Reddy, R. J.,* Kumari, A. H., and Kumar, J. J., Org. Biomol. Chem. 2021, 19, 3087-3118
[10]-Simple and Efficient Synthesis of Allyl Sulfones through Cs2CO3-mediated Radical Sulfonylation of Morita-Baylis–Hillman Adducts with Thiosulfonates, Shankar, A., Waheed, Md. and Reddy, R. J.* SynOpen, 2021, 5, 91–99 (Invited)
(Highlighted in the SynForm News and Top Cited Article 2022)
[9]-Synthesis and Applications of Sodium Sulfinates (RSO2Na): A Powerful Building Block for the Synthesis of Organosulfur Compounds (Review article), Reddy, R. J.,* and Kumari, A. H., RSC Adv., 2021, 11, 9130-9221
Selected as the Most Popular article and recognized as a Top 10% cited article in 2022.
[8]-Phenylboronic acid-catalyzed tandem construction of S–S and C–S bonds: a new method for the synthesis of benzyl disulfanylsulfone derivatives from S-benzyl thiosulfonates, Reddy, R. J.,* Waheed, Md., and Krishna, G. R., Org. Biomol. Chem. 2020, 18, 3243-3248.
[7]-Pd-Catalysed Annulation of beta-Iodovinyl Sulfones with 2-Halophenols: A General Route for the Synthesis of 3-Sulfonyl Benzofuran Derivatives, Reddy, R. J.,* Kumar, J. J., A. H. Kumari and G. R. Krishana, Adv. Synth. Catal. 2020, 362, 1317-1322.
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-----------------------------------:2018-2019:-------------------------------------
--: Publications during the Postdoc (UK, Japan, and Taiwan) and PhD (Univ. of Hyderabad):---
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18. Alkynyl thioethers in gold-catalysed annulations to form oxazoles
Reddy, R. J., Ball-Jones, M. P., and Davies, P. W., Angew. Chem. Int. Ed., 2017, 56, 13310–13316.
17. General Entry into o-,o’-Heteroatom-Linked N-(Hetero)aryl Imidazole Motifs by Gold-Catalysed Formal [3+2]-Dipolar Cycloaddition (designated as VIP)
Garzon, M., Arcea, E. M., Reddy, R. J. and Davies, P. W., Adv. Synth. Catal., 2017, 359, 1837-1843
16. Efficient and Flexible Synthesis of Highly Functionalised 4-Aminooxazoles by a Gold-Catalysed Intermolecular Formal [3+2] Dipolar cycloaddition (designated as VIP)
Gillie, A. D.,+ Reddy, R. J.,+ and Davies, P. W. (+equally contributed), Adv. Synth. Catal., 2016, 358, 226-239.
Reddy, R. J., Kawai, N., Uenishi, J., J. Org. Chem., 2012, 77, 11101–11108
14. Kinetic resolution of activated nitroallylic acetates with aldehydes and ketones via conjugate addition-elimination SN2' process
Reddy, R. J., Lee, P.-H., Magar, D. R., Chen, J.-H. and Chen, K., Eur. J. Org. Chem., 2012, 353-365.
13. Highly Efficient Organocatalytic Kinetic Resolution of Activated Nitroallylic Acetates with Aldehydes via Conjugate Addition-Elimination
Reddy, R. J. and Chen, K., Org. Lett., 2011, 13, 1458-1461.
12. Pyrrolidine-Camphor Derivatives as a New Class of Organocatalysts for Direct Asymmetric Michael Addition of Aldehydes and Ketones to β-Nitroalkenes
Ting, Y.-F., Chang, C., Reddy, R. J., Magar, D. R. and Chen, K., Chem. Eur. J., 2010, 16, 7030-7038
11. An efficient Morita-Baylis-Hillman reaction for the synthesis of multifunctional 2-hydroxy-3-nitrobut-3-enoate derivatives
Kuan, H.-H.,† Reddy, R. J.† and Chen, K. (†equally contributed), Tetrahedron 2010, 66, 9875-9879
10. The Baylis-Hillman adducts as a valuable source for one-pot multistep synthesis: A facile synthesis of 5-substituted-2-piperidones
Basavaiah, D., Reddy, R. J. and Lenin, D. V., Helv. Chim. Act., 2010, 93, 1180-1186
9. Remarkable reaction Rate and excellent enantioselective direct a-amination of aldehydes with azodicarboxylates catalyzed by pyrrolidinyl-camphor derived organocatalysts
Liu, P.-M., Chang, C., Reddy, R. J., Ting, Y.-F., Kuan, H.-H. and Chen, K., Eur. J. Org. Chem., 2010, 42-46
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8. Novel Prolinamide-Camphor Containing Organocatalysts for Direct Asymmetric Michael Addition of Unmodified Aldehydes to Nitroalkenes
Reddy, R. J., Kuan, H.-H., Chou, T.-Y., and Chen, K., Chem. Eur. J., 2009, 15, 9294-9298
7. ​Pyrrolidine-Camphor Derivative as an Organocatalyst for Asymmetric Michael Additions of a,a-Disubstituted Aldehydes to b-Nitroalkenes: Construction of Quaternary Carbon-Bearing Aldehydes under Solvent-Free Conditions
Chang, C., Li, S.-H., Reddy, R. J. and Chen, K., Adv. Syn. Catal., 2009, 351, 1273-1278
6. Highly diastereo- and enantio-selective direct aldol reactions promoted by water-compatible organocatalysts bearing a pyrrolidinyl-camphor structural scaffold
Tzeng, Z.-H., Chen, H.-Y., Reddy, R. J., Huang, C.-T., and Chen, K., Tetrahedron 2009, 65, 2879–2888
5. Simple and facile synthesis of tetralone-spiro-glutarimides and spiro-bis-glutarimides from Baylis-Hillman acetates
Basavaiah, D., and Reddy, R. J., Org. Biomol. Chem., 2008, 6, 1034-1039
4. The Baylis-Hillman reaction: a novel source for attraction, opportunities, and challenges in synthetic chemistry (Recognized as a Top 10% cited article in 2008)
Basavaiah, D, Rao, K. V. and Reddy, R. J., Chem. Soc. Rev. 2007, 36, 1581-1588
3. Applications of Baylis-Hillman adducts: A simple, convenient, and one-pot synthesis of 3-benzoylquinolines
Basavaiah D, Reddy, R. J. and Rao, J. S., Tetrahedron Lett., 2006, 47, 73-77
2. TiCl4 catalyzed tandem construction of C-C and C-O bonds: a simple and one-pot atom-economical stereoselective synthesis of spiro- oxindoles
Basavaiah, D., Rao, J. S., Reddy, R. J. and Rao, A. J., Chem. Commun., 2005, 2621-2623
1. Simple, facile and one-pot conversion of the Baylis-Hillman adducts into functionalized 1,2,3,4-tetrahydroacridines and cyclopenta-[b]quinolines
Basavaiah, D., Rao, J. S., and Reddy, R. J., J. Org. Chem., 2004, 69, 7379-7382
Books/Book Chapters, etc.
1. Cycloannulation strategies for the direct construction of 3-functionalized benzoheteroles (Book Chapter)
Reddy, R. J.,* A. H. Kumari and N. Sharadha, Targets in Heterocyclic Systems, 2023, Volume 27, pages 222-252
Italian Chemical Society, http://dx.medra.org/10.17374/targets.2024.27.222.
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2. Other 2-substituted pyrrolidines as asymmetric organocatalysts (Book Chapter)
Reddy, R. J. and Chen, K.* Sustainable Catalysis, 2015, Volume 2, Chapter 9, pp 200-235, Royal Society of Chemistry, ISBN: 9781782620570
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3. Applications of Baylis-Hillman adducts: A novel strategies for the synthesis of spiro and heterocyclic compounds (Book Monograph)
Reddy, R. J., LAMBERT Academic Publishing, 2012, ISBN-10:365921707
Laboratory of OrganoSulfur Chemistry
Dr. Raju J Reddy Research Group
Department of Chemistry, University College of Science
Osmania University, Hyderabad, India